TAG 45 is another popular SECONDARY anesthetic for use AFTER the skin is broken on all procedures. It is safe and effective. Ingredients: 4% Lidocaine with Epinephrine. TAG 45 is a great pain-killer for microblading, permanent makeup, tattooing, electrolysis, waxing or any other painful procedure. TAG 45 is similar to Duracaine but includes Epinephrine to reduce swelling and bleeding.